Physicochemical studies, residue studies, pharmacokinetic studies, biodegradation studies, efficacy studies of biocides.
- Statement of GLP compliance No 5/2009/GLP
| Evaluation of biological effectivity | ||
| No. | Study procedures | Normative documents |
1 |
Insecticide activity expressed asLD50 |
Own method |
2 |
Insecticide activity expressed as LC50 |
Own method |
3 |
Insecticide residual activity of aerosols and other ready-to-use form expressed as LT50 |
Own method |
4 |
Insecticide activity of pest bait |
Own method. |
5 |
Insecticide efficacy of sticky traps |
Own method |
6 |
Determination of insecticide efficacy of aerosols (in the room) |
Own method |
7 |
Determination of larvicidal activity |
Own method |
8 |
Examination of insecticidal efficacy of fumigation products |
Own method |
Determination of physical, chemical and technical properties of substances and chemical products |
||
| No. | Study procedures | Normative documents / own method |
1 |
Relative density of liquids and solids |
OECD 109, ISO 649/1 and ISO 649/2, ISO 758:1976, ISO 3507:1999, ISO 901:1976, ISO 787-10:1993, PN-92/C-0504; CIPAC MT 3 and EEC A.3 |
2 |
Determination of pH values |
PN-C-04665:2001 and CIPAC MT 75 |
3 |
Free acidity or alkalinity |
PN-C-04665:2001 and CIPAC MT 31 |
4 |
Kinematic and dynamic viscosity of Newtonian liquids |
OECD 114 and PN-EN ISO 3104: 2002 and PN-EN ISO 3105: 2002; PN-81/C-04011 |
5 |
Viscosity of Newtonian and non - Newtonian fluids |
PN-ISO 2555, PN-EN-ISO 3219:2000 and PN-EN 12092: 2004 ASTM D-2196-99 |
6 |
Determination of Weight Loss of Tested Material |
CIPAC MT 17 |
7 |
Ambient temperature storage procedure |
Technical Monograph GIFAP No 17 |
8 |
Accelerated storage procedure |
CIPAC MT 46 |
9 |
Low temperature (0°C) storage procedure |
CIPAC MT 39 |
10 |
Low temperature (0°C) stability testing of liquids |
CIPAC MT 39 |
11 |
Dilution stability |
CIPAC MT 41 and CIPAC MT 179 |
12 |
Pourability of suspension concentrates |
CIPAC MT 148 |
13 |
Wettability |
PN-87 C-04662 and CIPAC MT 53.3 |
14 |
Suspensibility |
PN-C-04654:1997 and CIPAC MT 15.1, MT 161 and MT 168 |
15 |
Emulsifiability, re-emulsifiability and emulsion stability, dispersion stability |
Own method based on PN-C-04652:1998 and CIPAC MT 36 |
16 |
Persistent foaming |
PN-85/C-04661 and CIPAC MT 47 |
17 |
Tap density |
CIPAC MT 33, 159 and 169. |
18 |
Dry sieve test |
PN-71/C-04501 and CIPAC MT 59.1 and CIPAC MT 58.2 |
19 |
Wet sieve test |
PN-71/C-04501 and CIPAC MT 59.3 and CIPAC MT 167; CIPAC MT 185 |
20 |
Dissolution rate of water soluble bags |
CIPAC MT 176 |
21 |
Packaging stability |
Technical Monograph GIFAP No 17 |
22 |
Pourability and effectiveness of cleaning procedures |
Own method |
23 |
Appearance |
Technical Monograph GIFAP No 17 . |
24 |
Determination of particle size distribution by Laser difraction |
CIPAC MT 187 ISO 13320-1;1999 |
25 |
Determination of the Spontaneity Dispersion of Suspension Concentrates |
CIPAC MT 160 |
26 |
Determination of Granular Product Dust Content |
CIPAC MT 171 |
27 |
Determination of pesticides solubility rate |
CIPAC MT 60 |
28 |
Determination of seed to seed uniformity of distribution for liquid seed-treatment formulations |
CIPAC MT 175. |
29 |
Flowability of granules |
CIPAC MT 172 |
30 |
Measurement of the surface tension of aqueous solutions |
OECD 115 EEC A.5 |
31 |
Evaluation of solubility of chemical substances |
OECD 105 |
32 |
Evaluation of solubility of chemical substances in organic solvents, shake flask method |
OECD 105 EEC A.6 |
33 |
Evaluation of partition coefficient n-octanol/water, shake flask method |
OECD 107 EEC A.8 |
34 |
Determination of the melting temperature |
OECD 102 EEC A1 |
35 |
Determination of the boiling temperature of substances using capillary tube in liquid bath, the Siwoloboff method |
OECD 103 EEC A2 |
36 |
Evaluation of rate constants of hydrolysis in water of chemical substances |
OECD 111 |
37 |
Evaluation of dissociation constants in water of chemical substances |
OECD 112 |
38 |
Determination of dissociation constants of chemical substances in water , |
OECD 112 |
39 |
Determination of dissociation constants of chemical substances in water, conductometric method |
OECD 112 |
40 |
Determination of crystallization temperature |
PN ISO 1392 |
41 |
Determination of the melting temperature of substances using capillary tube in metal block |
OECD 102 |
42 |
Determination of the boiling temperature of substances using capillary tube in metal block |
OECD 103 EEC A.2 |
43 |
Determination of chemical substances water solubility: column elution method |
OECD 105 EEC A.6. |
44 |
Determination of partition coefficient |
OECD 123 |
45 |
Determination of partition coefficient |
OECD 122 |
46 |
Phototransformation of chemicals in water - direct and indirect photolysis |
OECD 316 |
47 |
Photodegradation of chemical substances on soil |
OPPTS 835.2410 |
48 |
Determination of dry matter and water content in soil on a dry soil mass basis |
PN-ISO 11465 |
49 |
Thermal stability of chemical substances in air |
OECD 113 |
50 |
Refraction index determination |
Farmakopea Poland wyd. VI 2002 |
51 |
Determination of optical rotation of chemical substances |
Farmakopea Poland wyd. VI 2002 |
52 |
Accelerated ageing test of chemical substances and the mixtures of them at 400C and 75% relative humidity |
According to no 75/318/EEC directive, app. ICH Q1A |
53 |
Long term Accelerated ageing test of chemical substances and the mixtures of them at 250C and 60 % relative humidity |
According to no 75/318/EEC directive, app. ICH Q1A |
54 |
Determination of vapor pressures of substances using gas saturation method |
OECD 104 EEC A.4 |
55 |
Determination of vapor pressures of substances using static method |
OECD 104 EEC A.4 |
56 |
Determination of vapour pressures of substances using effusion method with Knudsen cell. |
OECD 104 EEC A.4 |
57 |
Determination of oxidizing properties of solids |
EEC A.4 |
58 |
Determination of oxidizing properties of solids |
EEC A.17 |
59 |
Determination of pyrophoric properties of solids and liquids |
EEC A.13 |
60 |
Determination of oxidizing properties of liquids |
EEC A.21 |
61 |
Determination of auto-ignition temperature (liquids) |
EEC A.15 |
62 |
Determining the minimum ignition temperatures of dust |
PN-EN 50281-2-1:2002-12 |
63 |
Flammability solids |
EEC A.10 |
64 |
Flash point |
EEC A.9 |
65 |
Determining the ability of solids to self-heating up to self-ignition |
EEC A.10 |
66 |
Determination of initial boiling point |
Test UN N.4 |
67 |
Determination of relative self-ignition temperature for solids |
PN-ISO 918 |
68 |
Explosive properties
|
EEC A.14 |
| Environmental studies | ||
No. |
Study procedures |
Normative documents |
1 |
Ready aerobic biodegradability screening test of substances using manometric respirometry |
OECD 301F EEC C.4-D |
2 |
Ready aerobic biodegradability screening test of substances using Dissolved Organic Carbon (DOC) die-away test |
OECD 301 A |
3 |
Ready aerobic biodegradability screening test of substances using closed bottle method |
OECD 301D |
4 |
Manometric respirometry measurement of biodegradation of substances in soil under aerobic conditions |
PN-ISO 11266 DIN 19737 |
5 |
Inherent aerobic biodegradability test of substances using Zahn-Wellens test |
OECD 302 B |
6 |
Acivated sludge simulation test |
OECD 303A |
7 |
Evaluation of the ultimate aerobic biodegradability and disintegration of packaging materials under controlled composting conditions - Method by analysis of released carbon dioxide |
PN-EN 14046 |
8 |
Activated sludge respiration inhibition test |
OECD 209 |
9 |
Ready biodegradability – CO2 in sealed vessels (Headspace Test) |
OECD 310 |
10 |
Anaerobic biodegradability of organic compounds in digested sludge, by measurement of gas production |
OECD 311 |
11 |
Determination of the ultimate aerobic biodegradability of plastic materials in an aqueous medium - Method by measuring the oxygen demand in a closed respirometer |
EN ISO 14851 |